Lotenol Gel

Indication

Lotenol sterile eye gel is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular surgery.

Dosage & Administration

Apply one to two drops of Lotenol gel into the conjunctival sac of the affected eye four times daily beginning the day after surgery and continuing throughout the first 2 weeks of the post-operative period.

Precautions

Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. If this product is used for 10 days or longer, IOP should be monitored.
Use of corticosteroids may result in posterior subcapsular cataract formation.
The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids.
Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infection. In acute purulent conditions, steroids may mask infection or enhance existing infection.
Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex).
Fungal infections- Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use.
Contact Lens Wear- Patients should not wear contact lenses during their course of therapy with Loteprednol Etabonate gel.

Use in Special Population
Use in Pregnancy:
Teratogenic Effects: Pregnancy Category C.
There are no adequate and well controlled studies in pregnant women. Loteprednol Etabonate gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in Lactating Mother:
It is not known whether topical ophthalmic administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Caution should be exercised when Loteprednol Etabonate gel is administered to a nursing woman.
Pediatric Use:
Safety and effectiveness in pediatric patients have not been established.
Geriatric Use:
No overall differences in safety and effectiveness have been observed between elderly and younger patients.