Indication

It is indicated for the prevention of ischemic events, myocardial infarction, stroke and cardiovascular death in patients with acute coronary syndrome.


Dosage & Administration

The recommended dose is one tablet once daily.


Precautions

General: As with other anti-platelet agents, Clopidogrel should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery, or other pathological conditions. If a patient is to undergo elective surgery and an antiplatelet effect is not desired, Clopidogrel should be discontinued 7 days prior to surgery. Hepatic or renal impairment patient: Should be avoided in patients with impaired hepatic and renal function. Aspirin causes sodium and water retention in patients with renal impairment and increases the risk of gastrointestinal bleeding. Pregnancy: Adverse effects are increased in the mother and the fetus following chronic ingestion of Aspirin. Because of possible adverse effects on the neonate and the potential for increased maternal blood loss, Aspirin and Clopidogrel should be avoided during the last three months of pregnancy. Nursing mothers: Clopidogrel and Aspirin should be avoided in nursing mothers because of the possible risk of developing Reye's syndrome. Regular use of high doses of Aspirin could impair platelet function and produce hypothrombinemia in infants if neonatal vitamin K levels are low. Pediatric use: Safety and effectiveness of Clopidogrel and Aspirin in the pediatric population have not been established.


Product Details


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