Kolosal™
Cholera Saline
Intravenous Infusion BP
Presentation
Kolosal™ 500 ml Intravenous Infusion: Each 100 ml solution contains Sodium Chloride BP 0.5 g, Potassium Chloride BP 0.1 g and Sodium Acetate (as Trihydrate) BP 0.393 g.
Kolosal™ 1000 ml Intravenous Infusion: Each 100 ml solution contains Sodium Chloride BP 0.5 g, Potassium Chloride BP 0.1 g and Sodium Acetate (as Trihydrate) BP 0.393 g.
Description
Kolosal™ w/v is a sterile & pyrogen free solution of Sodium Chloride, Potassium Chloride and Sodium Acetate (as Trihydrate) in Water for Injections.
Indications
Kolosal™ contains different electrolytes which are usually depleted in various conditions e.g. diarrhea, vomiting, profuse sweating etc. So, Kolosal™ is indicated in cholera, also in diarrhea, vomiting, and fluid loss to replenish and restore the normal electrolyte balance of the body.
Dosage and Administration
The volume and rate of infusion of Cholera Saline depends upon the requirements of the patient and the judgment of the physician. It usually varies with age, weight and clinical condition of the patient.
Side Effects
Malaise, low-grade fever, headache, generalized aches and pains, flushing, generalized urticaria, tachycardia and hypotension may occur. Reactions at the site of the injection may occasionally occur, usually within 5 to 7 days. These include erythema, swelling, pain, tenderness or induration.
Contraindications
Defer administration in the presence of acute respiratory or other active infections. Administration of saline to a patient taking corticosteroids or other immunosuppressive agents may result in an altered immune response and should be avoided if possible.
Precautions & Warning
Since Cholera Saline contains different electrolytes, it should be infused
with caution in patients where electrolyte imbalance may cause detrimental
effects, e.g. in pregnancy, renal impairment, heart failure, pulmonary
congestion, head injury etc. or in patients receiving potassium sparing
diuretics.
In Pregnancy: Pregnancy Category B. Infusion of fluid should be immediately
discontinued if rigor arises for any reason during the process. Do not use
if the solution is cloudy, contains particles, or after expiry date.
Pharmaceutical Precaution
Kolosal™ should be stored at controlled room temperature.
Commercial Pack
Kolosal™ 500 ml Intravenous Infusion: Available in 500 ml Polypropylene bag.
Kolosal™1000 ml Intravenous Infusion: Available in 1000 ml Polypropylene
bag.
Administration Procedure
1. Check infusion set and infusion solution prior to use
2. Pull moderately to tear off the protective cover of the Eurohead
(Picture-1)
3. Hold lightly the Eurohead but not the bag (Picture-2)
4. Open the flow regulator fully and hold the giving set on the top white
area, but not the membrane venting region (Picture-2)
5. Insert the spike of the administration set to the Eurohead and fit the
connector of the administration set firmly to the needle
(Picture-2)
6. Gradually allow the fluid to flow down to the needle tip and close
7. Remove the protective cover of the needle
8. Locate the venipuncture site and clean the site with an antiseptic
solution, and then insert the needle (Picture-3)
9. Securely tape the puncture site
10. Securely tape the wings and tubing
11. Start infusion while adjusting drip speed
