Glucolin™
Dextrose 5% w/v
Intravenous Infusion BP
Presentation
Glucolin™ 500 ml Intravenous Infusion: Each 100 ml solution contains Dextrose BP 5 g.
Glucolin™ 1000 ml Intravenous Infusion: Each 100 ml solution contains Dextrose BP 5 g.
Description
Glucolin™ w/v is a sterile & pyrogen free solution of Dextrose in Water for Injections.
Indications
Glucolin™ is administered in the treatment of carbohydrate and fluid depletions. It is mainly used to replace water deficiency and should be given alone when there is no significant loss of electrolytes. Water depletion (dehydration) tends to occur when these losses are not matched by a comparable intake, as for example may occur in coma or dysphagia or in the aged person who may not drink water in sufficient amount on their own initiative. It provides a readily metabolizable nutrient. One litre of 5% solution provides about 170 calories. Glucose solutions are also given in regimens with calcium bicarbonate, and insulin for the emergency management of hyperkalaemia. They are also given, after correction of hyperglycaemia, during treatment of diabetic ketoacidosis, when they must be accompanied by continuing insulin infusion. Glucolin™ infusion also may act as a suitable vehicle for the slow intravenous infusion of numerous drugs.
Dosage and Administration
The dose of Dextrose infusion is variable. It is dependent on individual patient requirements. For Dextrose 5% solution, the dose frequently ranges from 500 to 1000 ml. The maximum rate of infusion that will not cause glycosuria is 0.5 g/kg/hr. About 95% is retained when the rate is 0.8 g/kg/hr. the maximum rate of glucose utilization is about 800 mg/kg/hr.
Side Effects
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia. If these cases occur please discontinue the infusion.
Contraindications
Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Precautions & Warning
Serum glucose concentration should be carefully monitored. Concurrent use of insulin may be needed in case of diabetic patients. Dextrose solution should not be mixed with whole blood as haemolysis and clumping may occur. Infusion of fluid should be immediately discontinued if rigor arises for any reasons during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.
Pharmaceutical Precaution
Glucolin™ should be stored at controlled room temperature.
Commercial Pack
Glucolin™ 500 ml Intravenous Infusion: Available in 500 ml Polypropylene bag.
Glucolin™ 1000 ml Intravenous Infusion: Available in 1000 ml Polypropylene bag.
Administration Procedure
1. Check infusion set and infusion solution prior to use
2. Pull moderately to tear off the protective cover of the Eurohead (Picture-1)
3. Hold lightly the Eurohead but not the bag (Picture-2)
4. Open the flow regulator fully and hold the giving set on the top white
area, but not the membrane venting region (Picture-2)
5. Insert the spike of the administration set to the Eurohead and fit the
connector of the administration set firmly to the needle (Picture-2)
6. Gradually allow the fluid to flow down to the needle tip and close
7. Remove the protective cover of the needle
8. Locate the venipuncture site and clean the site with an antiseptic
solution, and then insert the needle (Picture-3)
9. Securely tape the puncture site
10. Securely tape the wings and tubing
11. Start infusion while adjusting drip speed
