Fructolin™
Fructose 10% w/v
Intravenous Infusion BP
Presentation
Fructolin™ 500 ml Intravenous Infusion: Each 100 ml solution contains Fructose BP 10 g.
Description
Fructolin™ 10% Infusion is a sterile & pyrogen free solution of Fructose in Water for Injections.
Indications
Fructolin™ 10% Infusion is used intravenously as a carbohydrate nutrient. It is converted to liver glycogen and metabolized more rapidly than dextrose without requiring insulin and thus may be used in diabetic patients. Fructose 10% Infusion is indicated in patients requiring fluid replacement and caloric feeding. It is better "nitrogen-sparer" than glucose.
Dosage and Administration
The volume and rate of infusion of fructose IV solution will depend upon the requirements of the patient and the judgement of attending physician. But the rate of infusion of fructose should not exceed 0.5-1 g/kg body weight per hour. The usual recommended flow rate for adult is 30-75 drops per minute infused intravenously.
Side Effects
Intravenous administration of fructose may cause lactic acidosis and hyperuricemia. The rapid infusion of fructose results in facial flushing, abdominal pain and sweating.
Contraindications
Fructose is contraindicated in certain inborn errors of fructose metabolism, methyl alcohol poisoning, hyperuricemia, liver failure, and lactic acidosis.
Precautions & Warning
Fructose should not be given to patients with hereditary fructose intolerance. It should be given with caution to patients with impaired kidney function or severe liver damage. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.
Pharmaceutical Precaution
Fructolin™ should be stored at controlled room temperature.
Commercial Pack
Fructolin™ 500 ml Intravenous Infusion: Available in 500 ml Polypropylene bag.
Administration Procedure
1. Check infusion set and infusion solution prior to use
2. Pull moderately to tear off the protective cover of the Eurohead (Picture-1)
3. Hold lightly the Eurohead but not the bag (Picture-2)
4. Open the flow regulator fully and hold the giving set on the top white
area, but not the membrane venting region (Picture-2)
5. Insert the spike of the administration set to the Eurohead and fit the
connector of the administration set firmly to the needle (Picture-2)
6. Gradually allow the fluid to flow down to the needle tip and close
7. Remove the protective cover of the needle
8. Locate the venipuncture site and clean the site with an antiseptic
solution, and then insert the needle (Picture-3)
9. Securely tape the puncture site
10. Securely tape the wings and tubing
11. Start infusion while adjusting drip speed
